{"id":4843,"date":"2024-06-19T16:35:01","date_gmt":"2024-06-19T14:35:01","guid":{"rendered":"https:\/\/www.progettomitofusina2.com\/?p=4843"},"modified":"2024-06-19T16:55:26","modified_gmt":"2024-06-19T14:55:26","slug":"4843","status":"publish","type":"post","link":"https:\/\/www.progettomitofusina2.com\/en\/4843\/","title":{"rendered":"WEBINAIRE CMT FRANCE:"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-lxlyakc2-95de378ef2dcb65e153702de401a84fd\">\n.avia-image-container.av-lxlyakc2-95de378ef2dcb65e153702de401a84fd img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-lxlyakc2-95de378ef2dcb65e153702de401a84fd .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-lxlyakc2-95de378ef2dcb65e153702de401a84fd av-styling- avia-align-center  avia-builder-el-0  el_before_av_heading  avia-builder-el-first '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-4817 avia-img-lazy-loading-not-4817 avia_image ' src=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/cmt-france.jpg\" alt='' title='cmt france'  height=\"630\" width=\"1500\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/cmt-france.jpg 1500w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/cmt-france-300x126.jpg 300w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/cmt-france-1030x433.jpg 1030w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/cmt-france-768x323.jpg 768w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/cmt-france-705x296.jpg 705w\" sizes=\"(max-width: 1500px) 100vw, 1500px\" \/><\/div><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-lxlybizd-7ea395854a1e3f5d51f50c39e1ac1e3a\">\n#top .av-special-heading.av-lxlybizd-7ea395854a1e3f5d51f50c39e1ac1e3a{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-lxlybizd-7ea395854a1e3f5d51f50c39e1ac1e3a .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-lxlybizd-7ea395854a1e3f5d51f50c39e1ac1e3a .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-lxlybizd-7ea395854a1e3f5d51f50c39e1ac1e3a av-special-heading-h2 blockquote modern-quote  avia-builder-el-1  el_after_av_image  el_before_av_textblock '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >WEBINAIRE CMT FRANCE: DYNAMISM OF RESEARCH<\/h2><div class='av-subheading av-subheading_below'><p>15 June 2024<\/p>\n<\/div><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<section  class='av_textblock_section av-lxlya06u-23e38d875078694b4b24bebccf2de7e6 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><p><span class=\"ng-star-inserted\" data-index=\"2\">Last Saturday, June 15, 2024 we attended the webinar organized by the CMT FRANCE association entitled &#8220;Dynamism of research on the CMT in France&#8221;.<\/span><\/p>\n<p><span class=\"ng-star-inserted\" data-index=\"3\">It was very interesting to hear the intervention of authoritative French specialists introduced by Alexandre Hoyau, President of CMT France , whom we thank for the invitation to attend.<\/span><\/p>\n<p><span class=\"ng-star-inserted\" data-index=\"4\">In particular, Prof. Attarian explained the complicated situation of neuromuscular diseases in France, which consist of 700 forms of rare neuromuscular diseases (spinal amyotrophies, muscle diseases, peripheral nerve diseases, mitochondrial diseases, diseases of neuromuscular transmission) of which about 60 thousand people are affected. <\/span><span class=\"ng-star-inserted\" data-index=\"5\">The diagnosis, research and management are coordinated by the Filnemus network, consisting of 10 commissions with 24 doctors responsible for action groups throughout France. <\/span><span class=\"ng-star-inserted\" data-index=\"6\">One of their priorities is to develop translational research within the network.<\/span><\/p>\n<p><span class=\"ng-star-inserted\" data-index=\"7\">The interventions were largely related to research on the CMT1A, the most frequent type, which have many treatment prospects underway; <\/span><span class=\"ng-star-inserted\" data-index=\"8\">but we also talked of the reasons why research times are so long, about studies on CMT4H due to mutations in the FGD4\/FRABIN gene, on the discovery of the COQ7 gene, therapeutic strategies for CMT with STOP mutations and about the use of curcumin as a possible cure (for CMT1A)a possible siRNA therapeutic strategy for CMT1A.<\/span><\/p>\n<p><strong>The most interesting intervention was the one of Dr Nathalie Bernard-Marissal, researcher of INSERM (National Institute of Health and Medical Research) &#8211; University of Aix-Marseille (dip. Translazional Neuromyology) about scientific research for the CMT2A. He briefly mentioned the currently developing therapeutic approaches that are: an axonal transport booster with the inhibitor HDAC6 (Picci , 2020); a cell fusion activator peptide&#8221;(Franco A. 2020); stop axon degeneration with neuroprotector SARM1 (Sato-Yamada 2022).<\/strong><\/p>\n<p><strong>With our great satisfaction, he mentioned our research project with gene therapy, conducted at the Dino Ferrari Center by the team of Prof Corti with Dr Rizzo, as the most interesting and promising therapeutic approach, which is also being tested at their research group.<\/strong><\/p>\n<p>For us it is a good news, both because it confirms the validity of our project, and because we could get synergies between the two study groups, as already exists between our association and the CMT association of our dear friends across the Alps, with whom we have been working effectively for years.<\/p>\n<p>For any further information on the topic, please refer to the CMT France website and for any questions (including translation) you can contact us.<\/p>\n<p><a href=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/Programme_Webinaire_Recherche_15_juin_2024.pdf\">Programme_Webinaire_Recherche_15_juin_2024<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4821\" src=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/1-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1441\" srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/1-scaled.jpg 2560w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/1-300x169.jpg 300w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/1-1030x580.jpg 1030w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/1-768x432.jpg 768w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/1-1536x865.jpg 1536w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/1-2048x1153.jpg 2048w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/1-1500x845.jpg 1500w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/1-705x397.jpg 705w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4823\" src=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/2-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1441\" srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/2-scaled.jpg 2560w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/2-300x169.jpg 300w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/2-1030x580.jpg 1030w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/2-768x432.jpg 768w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/2-1536x865.jpg 1536w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/2-2048x1153.jpg 2048w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/2-1500x845.jpg 1500w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/2-705x397.jpg 705w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4825\" src=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/3-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1441\" srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/3-scaled.jpg 2560w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/3-300x169.jpg 300w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/3-1030x580.jpg 1030w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/3-768x432.jpg 768w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/3-1536x865.jpg 1536w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/3-2048x1153.jpg 2048w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/3-1500x845.jpg 1500w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/3-705x397.jpg 705w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4827\" src=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/4-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1441\" srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/4-scaled.jpg 2560w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/4-300x169.jpg 300w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/4-1030x580.jpg 1030w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/4-768x432.jpg 768w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/4-1536x865.jpg 1536w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/4-2048x1153.jpg 2048w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/4-1500x845.jpg 1500w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/4-705x397.jpg 705w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4829\" src=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/5-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1441\" srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/5-scaled.jpg 2560w, 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srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/6-scaled.jpg 2560w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/6-300x169.jpg 300w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/6-1030x580.jpg 1030w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/6-768x432.jpg 768w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/6-1536x865.jpg 1536w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/6-2048x1153.jpg 2048w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/6-1500x845.jpg 1500w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/6-705x397.jpg 705w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4833\" src=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/7-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1441\" srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/7-scaled.jpg 2560w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/7-300x169.jpg 300w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/7-1030x580.jpg 1030w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/7-768x432.jpg 768w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/7-1536x865.jpg 1536w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/7-2048x1153.jpg 2048w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/7-1500x845.jpg 1500w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/7-705x397.jpg 705w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4835\" src=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/8-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1441\" srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/8-scaled.jpg 2560w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/8-300x169.jpg 300w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/8-1030x580.jpg 1030w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/8-768x432.jpg 768w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/8-1536x865.jpg 1536w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/8-2048x1153.jpg 2048w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/8-1500x845.jpg 1500w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/8-705x397.jpg 705w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4837\" src=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/9-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1441\" srcset=\"https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/9-scaled.jpg 2560w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/9-300x169.jpg 300w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/9-1030x580.jpg 1030w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/9-768x432.jpg 768w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/9-1536x865.jpg 1536w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/9-2048x1153.jpg 2048w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/9-1500x845.jpg 1500w, https:\/\/www.progettomitofusina2.com\/wp-content\/uploads\/2024\/06\/9-705x397.jpg 705w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/p>\n<\/div><\/section>\n","protected":false},"excerpt":{"rendered":"<p>June 15, 2024<br \/>\nLast Saturday we attended the webinar organized by the association CMT FRANCE entitled &#8220;Dynamism of research on the CMT in France&#8221;.<\/p>\n","protected":false},"author":2,"featured_media":4844,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[75,98,63],"tags":[],"class_list":["post-4843","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-2022-en","category-2023-news-and-events","category-news-and-events"],"_links":{"self":[{"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/posts\/4843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/comments?post=4843"}],"version-history":[{"count":4,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/posts\/4843\/revisions"}],"predecessor-version":[{"id":4852,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/posts\/4843\/revisions\/4852"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/media\/4844"}],"wp:attachment":[{"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/media?parent=4843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/categories?post=4843"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/tags?post=4843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}