{"id":2107,"date":"2022-04-27T09:30:10","date_gmt":"2022-04-27T07:30:10","guid":{"rendered":"https:\/\/www.progettomitofusina2.com\/portfolio-articoli\/database-mutazioni-mfn2\/"},"modified":"2022-10-21T12:46:23","modified_gmt":"2022-10-21T10:46:23","slug":"database-of-mitofusin2-mutations","status":"publish","type":"portfolio","link":"https:\/\/www.progettomitofusina2.com\/en\/portfolio-articoli\/database-of-mitofusin2-mutations\/","title":{"rendered":"DATABASE OF MITOFUSIN2 MUTATIONS"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-l2ionxa2-29cdb2ff2f458ada38dd4a1dd37ed5e4\">\n#top .av-special-heading.av-l2ionxa2-29cdb2ff2f458ada38dd4a1dd37ed5e4{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-l2ionxa2-29cdb2ff2f458ada38dd4a1dd37ed5e4 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-l2ionxa2-29cdb2ff2f458ada38dd4a1dd37ed5e4 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-l2ionxa2-29cdb2ff2f458ada38dd4a1dd37ed5e4 av-special-heading-h2 blockquote modern-quote  avia-builder-el-0  el_before_av_one_full  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >DATABASE OF MITOFUSIN2 MUTATIONS<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<div  class='flex_column av-av_one_full-a93934ecd89fbb8a9566d39e89cd3725 av_one_full  avia-builder-el-1  el_after_av_heading  avia-builder-el-last  first flex_column_div  '     ><section  class='av_textblock_section av-l2ipv1bc-95e8a855769d49230d86ccc881d6f0de '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><table style=\"border: 1px solid #ffffff; width: 1081px; height: 14369px;\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\" align=\"left\">\n<tbody>\n<tr>\n<td style=\"background-color: #8aa0c3; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; color: #ffffff; text-align: center;\">Exon<\/p>\n<\/td>\n<td style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3;\" align=\"center\">Protein change<\/p>\n<\/td>\n<td style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3;\" align=\"center\">Inheritance<\/p>\n<\/td>\n<td style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3;\" align=\"center\">Ethnicity<\/p>\n<\/td>\n<td style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3;\" align=\"center\">Onset age<\/p>\n<\/td>\n<td style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3;\" align=\"center\">Symptoms at onset<\/p>\n<\/td>\n<td style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3;\" align=\"center\">Reference<\/p>\n<\/td>\n<td style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; color: #ffffff; text-align: center; background-color: #8aa0c3;\" align=\"center\">Additional remarks<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Glu 288 Asp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">22-29y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">weakness and sensory<br \/>\nloss in the anterior<br \/>\ncompartments<br \/>\nof both legs foot drop<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Bergamin et al., 2014<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Ataxic steppage, gait,<br \/>\nsevere lower limb atrophy,<br \/>\nweakness, and Areflexia;<br \/>\nsensory\u2013motor axonal<br \/>\npolyneuropathy<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr356A<\/strong> <strong>la<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chinese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8-16y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Foot deformities,<br \/>\nsevere muscle atrophy,<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Wang et al., 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg104Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">German<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">slowly progressive<br \/>\nmotor and sensory<br \/>\npolyneuropathy<br \/>\nin childhood<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Brockmann et al., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">One patient with gait disturbance,<br \/>\nincreased OT reflexes, optic atrophy,<br \/>\nsaccadic interruption of horizontal<br \/>\neye movements, secondary<br \/>\nmacrocephaly, impaired hand<br \/>\nfunction, abnormal MRI;<br \/>\none patients with gait disturbance,<br \/>\noptic atrophy, impaired<br \/>\nhand function, normal MRI<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">9<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ser378Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">German<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Slowly progressive<br \/>\nmotor and sensory<br \/>\npolyneuropathy<br \/>\nin childhood<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Brockmann et al., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Gait disturbance,<br \/>\nincreased OT reflexes,<br \/>\nnormal MRI<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>IVS5-1G&gt;C<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">German<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Slowly progressive<br \/>\nmotor and sensory<br \/>\npolyneuropathy<br \/>\nin childhood<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Brockmann et al., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Gait disturbance,<br \/>\nsecondary macrocephaly,<br \/>\nabnormal MRI<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>\u00a0Arg94Gln<br \/>\n(<\/strong><strong>heterozygous<br \/>\nmutations)\u00a0<\/strong><\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Foot drop<br \/>\nand gait disturbance<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Kijima et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT2 phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Phe223Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Walking difficulties<br \/>\nand leg pain<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Kijima et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Congenital dislocation of the hip<br \/>\nand mild mental retardation,<br \/>\nfatty, sleep apnea and classical<br \/>\nCMT2 phenotype<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr236Met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Running difficulties<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Kijima et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT2 phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Val244Met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 m<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">walking difficulties<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Kijima et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT2 phenotype<br \/>\nwith no sensory impairments<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Phe284Tyr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">pes cavus<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Kijima et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">slowly progressive muscle<br \/>\nweakness of lower legs, atrophy<\/p>\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">in the lower extremities,<br \/>\nno sensory impairments<br \/>\nand no decreased tendon reflexes<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Lys357Asn<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 m<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Frequent falls<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Kijima et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT2 phenotype<br \/>\nwith no sensory impairments<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Glu424Gly<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">congenital hearing loss<br \/>\nof the right ear and<br \/>\npain in the lower<br \/>\nextremities<br \/>\nduring exercise<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Kijima et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">severe leg pain at work, drop feet,<br \/>\nCMT2 phenotype with mildly<br \/>\ndecreased sensitivity to vibration,<br \/>\nnormal or slightly elevated<br \/>\ndeep tendon reflexes<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg259Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Caucasian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">19 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">progressive leg<br \/>\nweakness<br \/>\nand numbness<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Ajroud-Driss et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT2 phenotype with brisk deep<br \/>\ntendon reflexes except<br \/>\nfor the ankle jerks that<br \/>\nwere depressed.<br \/>\nHe had bilateral Hoffman<br \/>\nsign with normal tone<br \/>\nand flexor plantar response<strong>.<\/strong><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gly127Asp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">16 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lower limbs muscles weakness,<br \/>\nsensory loss (pain&gt;vibration),<br \/>\nextensor plantar responses<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His165Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 and 50 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild muscular weakness, pain and<br \/>\nvibration sensory loss,<br \/>\ntremor, SNHL, hoarseness<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His165Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild muscular weakness,<br \/>\npain and vibration sensory loss<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr362Met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">42 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild lower extremities<br \/>\nmuscle weakness and atrophy,<br \/>\ntransient sensory loss<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Met376Thr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">39 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild muscular weakness,<br \/>\npain and vibration sensory loss<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ala164Val<\/strong><\/p>\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr362Met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial, CH<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Falls<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Nicholson et al., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Slightly deaf, CMT2 phenotype with<br \/>\nupper and lower limbs involvement<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Asp214Asn<\/strong><\/p>\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Cys390Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial, CH<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Talipes<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Nicholson et al., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT2 phenotype with upper<br \/>\nand lower limbs involvement<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg707Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Clubfoot<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Nicholson et al., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Slightly deaf, Lipodystrophy<strong>,<br \/>\n<\/strong>CMT2 phenotype<br \/>\nwith upper and lower limbs<br \/>\ninvolvement<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu92Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Unknown<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Belgium<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">nerve biopsy revealed a similar loss<br \/>\nof large myelinated<br \/>\nfibres with even low evidence<br \/>\nof regeneration<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg100Gly<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Bulgaria<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Pro123Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Germany<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sural nerve biopsy with an apparent<br \/>\nloss of large myelinated nerve fibres<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His165Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Serbia<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His165Tyr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Czech Republic<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg250Trp Arg400X<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Unknown<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Poland<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg250Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Unknown<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Belgium<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">21 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">9<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His277Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Germany<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y; 15 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">parkinsonism occurred<br \/>\nat older age<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Met376Ile<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Czech Republic<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">35 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu379_Met381del<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">USA<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gln386Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">De novo<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Israel<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1.5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">18<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu710Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Unknown<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Bulgaria<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">19<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gln751X<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">De novo<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Czech Republic<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">19<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gln751<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Belgium<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His128Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">De novo<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Severe and asymmetrical<br \/>\nphenotype<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ser156Ile<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">9<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His277Tyr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&gt; 10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al. 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate phenotype<br \/>\nwith pyramidal signs,<br \/>\nvasomotor troubles<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al. 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Severe phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Severe phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">17<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&gt; 10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">19<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Phe665Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate and<br \/>\nasymmetrical phenotype<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Trp740Cys<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild phenotype<br \/>\nwith pyramidal signs<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">19<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Trp740Cys<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate and asymmetrical<br \/>\nphenotype with pyramidal signs,<br \/>\nvasomotor troubles, tremor<\/p>\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu745Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&gt; 10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild phenotype<br \/>\nand vasomotor problems<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">19<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu745Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familail<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&gt; 10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Met747Thr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">De novo<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Calvo et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Lys38del<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial, CH<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Italian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Foot drop<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Polke et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Val69Phe<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Turkey<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5-15 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2004<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu76Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">European<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7-44 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2004<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu92Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">McCorquodale et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu92Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Severe phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gly<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gly<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score: moderate<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gly<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score: severe<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Russia<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6-17 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2004<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score: moderate<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japan<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3-15 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2004<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chinese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Zhang et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score: severe<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Germany<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Neusch et al., 2007<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Norwegian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Stumble<br \/>\nand dorsal toes<br \/>\nweakness<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Braathen et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early-onset CMT2 with<br \/>\nno central nervous<br \/>\nsystem pathology<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">I decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Severe sensory<br \/>\nand motor<br \/>\nneuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010;<\/p>\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Banchs et al., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">AfroAmerican<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3-8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">optic atrophy<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nmoderate<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korea<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Frequent fall,<br \/>\nweakness in LE<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Cho et al., 2007<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Norwegian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">weakness in LE<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Braathen et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">One pt with CMT1 phentype,<br \/>\none pt with weakness in legs<br \/>\nand pes cavus<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">I decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate<br \/>\nsensory\/motor<br \/>\nneuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">China<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">progressive distal limb<br \/>\nmuscle<br \/>\nweakness and wasting<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lv et al., 2013<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gly103TrpfsX41<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">22 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Classic CMT2 phenotype,<br \/>\nmoderate instability<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sivera et al., 2013<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg104Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Italy<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y; 4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Awkward walk with<br \/>\nfrequent falling<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Del Bo et al., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg104Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">isolated case,<br \/>\nde novo<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Progressive weakness<br \/>\nin his legs<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Genari et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Cognitive impairment may<br \/>\nbe another feature of the<br \/>\nMFN2-related phenotype.<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg104Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">isolated case,<br \/>\nde novo<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Greek<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Developmental delay<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Baets et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Severe and early onset<br \/>\naxonal neuropathy<br \/>\nplus learning problems,<br \/>\nobesity, glucose intolerance,<br \/>\nleukoencephalopathy,<br \/>\nbrain atrophy,<br \/>\nevidence of myelin involvement<br \/>\nand mitochondrial structural<br \/>\nchanges on sural nerve biopsy.<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg104Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Childhood<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Abe et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr105Met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr105Met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">USA<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lawson et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score: mild<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">IV5<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr105LeufsX2<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korea<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">31 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">late-onset AD mild<br \/>\naxonal CMT<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Park et al., 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gly127Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Germany<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">48 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">weakness in LE<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Engelfried et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">double mutation in CIS<br \/>\nwith c.668T&gt;A<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Asn131Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Turkey<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">severe and typical early<br \/>\nonset CMT1<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Fischer et al., 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Cys132Thr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chinese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Zhang et al., 2009<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu146Phe<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Northern European,<br \/>\nCherokee American<br \/>\nIndian descent<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Klein et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr159_Gln162del<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Han Chinese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">13 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lin et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">intron5<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">intron5<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr159_Gln162del<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Taiwan<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">13 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lin et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">del intron 5-ex6<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Val160fsX26<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">French<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">axonal degeneration,<br \/>\nmyelin modifications,<br \/>\nand intra-axonal<br \/>\nmitochondria<br \/>\nwith distorted cristae<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Vital et al., 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His165Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Italian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Weakness, mild distal<br \/>\nleg sensory loss<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Marchesi et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Simultaneous heterozygous<br \/>\nMFN2 and GDAP1 mutations<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His165Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Co-occurence of ALS<br \/>\nand CMT2A<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His165Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">16 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Weakness in LE<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Cho et al., 2007<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ile203met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">II decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate<br \/>\nsensory\/motor<br \/>\nneuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr206Ile<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">European<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">tremor<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Asp210Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Tunisian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">LL weakness + visual,<br \/>\nhearing deficit<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Rouzier et al., 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ile213Thr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">USA<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lawson et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">mDNA instability + optic<br \/>\natrophy \u2018plus\u2019 phenotype<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Phe216Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial, CH<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">British<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12-18 m<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Foot drop<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Polke et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu218Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Norwegian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Ostern et al., 2013<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">del ex7-8<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial, CH<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">British<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12-18 m<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Foot drop<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Polke et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Phe223Tyr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korea<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">31 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">late-onset AD mild<br \/>\naxonal CMT<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Park et al., 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu233Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Taiwan<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lin et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">double mutation in CIS<br \/>\nwith c.474+4A&gt;G<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu248Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu248Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nmoderate<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu233Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Han Chinese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lin et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere; profound<br \/>\nproprioception loss<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ser249Phe<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Childhood<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Abe et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg250Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">McCorquodale et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Pro251Ala<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Italy<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8-50 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2004<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Pro251Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Pro251Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nmoderate<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Pro251Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">McCorquodale et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere; profound<br \/>\nproprioception loss<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Pro251Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">25 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Classic CMT2 phenotype<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sivera et al., 2013<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Wheelchair<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Asn252Lys<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">II decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Severe sensory<br \/>\nand motor neuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ser263Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korea<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">13 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Weakness in LE<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Cho et al., 2007<\/p>\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Val273Gly<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">USA<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lawson et al., 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">9<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gln276Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">European<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gln276His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chinese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">9 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Steppage gait;<br \/>\nprogressive distal muscle<br \/>\nweakness and atrophy<br \/>\nin lower and upper limbs<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Ching et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">9<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gln276His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">III decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild sensory<br \/>\nand motor neuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010;<\/p>\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Banchs et al., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Intrafamilial variability<br \/>\nwas observed<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">9<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg280His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">European<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11-35 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2004<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg280His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Vinci et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg280His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Severe lower-limbs sensory<br \/>\nworsening with loss of<br \/>\nindependent ambulation<br \/>\nafter epidural anesthesia<br \/>\nfor hip osteo-synthesis,<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">9<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gly298Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">II decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate<br \/>\nsensory\/motor<br \/>\nneuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">9<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Glu308X<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial, CH<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">British<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14 months<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Difficulty walking<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Polke et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gl<\/strong> <strong>u347Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Germany<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">childhood<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Engelfried et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Nonsense-mediated decay<br \/>\nin MFN2 transcripts<br \/>\nsequencing<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ser350Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ser350Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korea<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Gait abnormality<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Cho et al., 2007<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr356Ala<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">China<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Hollow foot,<br \/>\nclaw hand deformity,<br \/>\nand severe muscle<br \/>\natrophy of the lower<br \/>\nand upper<br \/>\ndistal extremities<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Wang et al., 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His361Tyr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">European<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His361Tyr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr362Met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial, CH<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Italian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Foot drop<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Polke et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">European<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere; profound<br \/>\nproprioception loss<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Taiwan<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lin et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Taiwan<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lin et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Han Chinese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lin et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Han Chinese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lin et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">China<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">progressive distal limb<br \/>\nmuscle weakness<br \/>\nand wasting<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lv et al., 2013<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">III decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate<br \/>\nsensory\/motor<br \/>\nneuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Banchs et., 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">22 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">slowly progressive<br \/>\nmuscle atrophy<br \/>\nand weakness of distal<br \/>\nextremities and<br \/>\nsteppage gait<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Takahashi et al., 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg364Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">patient with axonal<br \/>\nneuropathy and<br \/>\noptic atrophy<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Met376Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">26 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">McCorquodale et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere; profound<br \/>\nproprioception loss<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Met376Ile<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Germany<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">22 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Muscle cramps in LE<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Engelfried et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">11<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Met376Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">III decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Severe sensory<br \/>\nand motor neuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Cys390Phe<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 yr<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et l., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg400Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">isolated case<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Italian\/Irish<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">&lt; 1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">delayed motor<br \/>\nmilestones<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Baets et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg418X<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">European<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Parental mosaicism<br \/>\nin asymptomatic mother<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg418X<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Korean<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Axonal neuropathy<br \/>\nwith optic atrophy<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial,<br \/>\nassociated to<br \/>\nGDAP1 mutation<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spanish<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">severe distal muscle<br \/>\nweakness<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Cassereau et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">early onset CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Childhood<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">McCorquodale et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">III decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate<br \/>\nsensory\/motor<br \/>\nneuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">This variant may represent<br \/>\nrare benign polymorphism<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">III decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild sensory<br \/>\nand motor neuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">V decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Moderate<br \/>\nsensory\/motor<br \/>\nneuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">V decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild sensory<br \/>\nand motor neuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">V decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild sensory<br \/>\nand motor neuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Spain<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">V decade<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Mild sensory<br \/>\nand motor neuropathy<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Casasnovas et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Germany<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">26 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">paraeshesia in LE<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Engelfried et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg468His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Norwegian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Foot deformity<br \/>\nand stumbled<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Braathen et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT1 phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">15<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg519Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Familial, CH<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">British<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14 m<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Difficulty walking<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Polke et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">15<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Asn570Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Norwegian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">63 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Right foot<br \/>\nweakness+walking<br \/>\ndifficulties<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Braathen et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">dHMN phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">18<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Val705Ile<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">McCorquodale et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">dHMN phenotype<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Val705Ile<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Germany<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">foot deformities<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Engelfried et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">18<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Val705Ile<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Norwegian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Weakness in legs<br \/>\nand pes cavus<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Braathen et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">18<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Val705Ile<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Norwegian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">47 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Paresthesia in feet<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Braathen et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">18<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg707Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Norwegian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">44 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Muscular pain during<br \/>\nexercise in left leg<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Braathen et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">18<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg707_Asn709del<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">McCorquodale et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Intermediate CMT<\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ala716Thr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">18<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ala716Thr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Norwegian<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">23 and 50 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Recurrent ankle sprains,<br \/>\nweakness and<br \/>\nreduced balance<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Braathen et al., 2010<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">One with intermediate CMT<br \/>\nwith severe CMT neuropathy<br \/>\nscore, one with<br \/>\nparesthesia in foot<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu724Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Japanese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">childhood<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Luigetti et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ala738Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">isolated case<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">35 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Difficulty walking<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Luigetti et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">19<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ala738Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Italy<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">35 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">walking difficulties<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Luigetti et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Non consanguineous<br \/>\nhealthy parents<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">19<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Trp740Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">European<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5-52 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Z\u00fcchner et al., 2004<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Trp740Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">16 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Trp740Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">33 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nmoderate<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Trp740Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nmild<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Trp740Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">15 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nmoderate<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Trp740Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">China<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lv et al., 2013<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nmild<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Glu744Met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Han Chinese<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lin et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>His750Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">familial<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">6 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Tyr752X<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">sporadic<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely et al., 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu753<\/strong> <strong>fs<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Germany<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">62 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">gait ataxia<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Engelfried et al., 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">CMT neuropathy score:<br \/>\nsevere; profound<br \/>\nproprioception loss<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Gly<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely SME, 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg94Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Pipis M, 2020<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg95Gly<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">31 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Dankwa L, 2019<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Lys98Glu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Australia<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Vallat JM, 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ala100Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">45 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven K, 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg104Gln<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Pipis M, 2020<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\">may cause neurodevelopmental delay<\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg104Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Tunisia<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sitarz K, 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr105Ala<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Tunisia<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sitarz K, 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Lys109Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">sporadic<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Japan<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">impossible to run<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Ando M, 2017<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Asn131Thr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Pipis M, 2020<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ala166Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Chinese<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">27 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sun B, 2017<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Cys217Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Chinese<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Clubfoot<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Xie Y, 2016<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr232Asn<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Tunisia<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Sitarz K, 2012<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Phe240Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">3 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Amiott E, 2008<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Phe241Leu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Pipis M, 2020<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Val244Met<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">sporadic<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Japanese<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Foot drop<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Kijima K, 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu248Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely SME, 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu248His<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">2 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely SME, 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ser249Thr<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Japanese<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Abe A, 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ser249Cys<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Japanese<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Abe A, 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Pro251Ser<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Beaudonnet<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Arg259Cys<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">sporadic<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14-40 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Bombelli F, 2014<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ser263Phe<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Korean<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">45 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Chung KW, 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Glu288Lys<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Italian<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">29 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Bergamin C, 2016<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Lys307Glu<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">sporadic<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Chinese<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">7 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Xie Y, 2016<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Lys357Asn<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">sporadic<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Japanese<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">4 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Foot drop<\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Kijima K, 2005<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Thr362Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">32 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Pipis M, 2020<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Ala383Val<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Italian<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">10-50 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Muglia M, 2007<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Gln386Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">sporadic<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">1.5 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Verhoeven K, 2006<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu673Pro<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">12 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Pipis M, 2020<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Trp740Arg<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">5-6 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Lv H, 2013<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Leu741Trp<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">24 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Dankwa L, 2019<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Glu744Lys<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\">familial<\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\">Korean<\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">8 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Choi B-O, 2015<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<tr style=\"font-size: 12px; text-align: center;\">\n<td style=\"background-color: #b9e2fd; width: 66px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 134px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\"><strong>Tyr752X<\/strong><\/p>\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 114px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #cdedfd; width: 162px;\" nowrap=\"nowrap\"><\/td>\n<td style=\"background-color: #b9e2fd; width: 61px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">14 y<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 155px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">\n<\/td>\n<td style=\"background-color: #b9e2fd; width: 90px;\" nowrap=\"nowrap\">\n<p style=\"font-size: 12px; text-align: center;\" align=\"center\">Feely SME, 2011<\/p>\n<\/td>\n<td style=\"background-color: #cdedfd; width: 280px;\" nowrap=\"nowrap\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"font-size: 12px;\">\n<\/div><\/section><br \/>\n<section  class='av_textblock_section av-l2irbbt4-873b47769bc1df4e3149575a8dc5e9d5 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>AD: autosomic dominant \u00a0| \u00a0CH: compound heterozygous \u00a0| \u00a0LL: lower limbs<\/p>\n<\/div><\/section><\/p><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":1589,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"portfolio_entries":[78],"class_list":["post-2107","portfolio","type-portfolio","status-publish","has-post-thumbnail","hentry","portfolio_entries-disease-research"],"_links":{"self":[{"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/portfolio\/2107","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/portfolio"}],"about":[{"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/types\/portfolio"}],"author":[{"embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/comments?post=2107"}],"version-history":[{"count":7,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/portfolio\/2107\/revisions"}],"predecessor-version":[{"id":3560,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/portfolio\/2107\/revisions\/3560"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/media\/1589"}],"wp:attachment":[{"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/media?parent=2107"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/tags?post=2107"},{"taxonomy":"portfolio_entries","embeddable":true,"href":"https:\/\/www.progettomitofusina2.com\/en\/wp-json\/wp\/v2\/portfolio_entries?post=2107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}